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The company

Founded in 2005, Biom'up, a specialist in collagen-based absorbable medical devices for biosurgery, is developing a new generation hemostatic product composed of patent-protected biopolymers.

With broad expertise in biomaterials, Biom'up is creating innovative and clinically proven products that are used in many surgical specialties such as cardiothoracic and general surgeries.

Biom'up is committed to the design, development, and delivery of novel, high-performing solutions that make life easier for surgeons and better for patients.

Christian Gagnieu Dr. Christian Gagnieu

A Key Opinion Leader in the field of biopolymers for medical applications, Dr Christian Gagnieu was a researcher at the INSA Lyon Engineering School and Research Manager at the Lyon Pharmacy Faculty. Dr Gagnieu has collaborated with many companies in the medical field as an expert in biomaterials in general and in resorbable polymers in particular. Biom'up was founded on the basis of the development of his research.

Biom'up: Key Timeline Dates


Biom’up receives FDA marketing approval for

Completion of the pivotal clinical study assessing HEMOBLAST™ Bellows in the U.S.A.

European launch

Biom’up launches its IPO on the Euronext regulated market in Paris and raise 38,1 M€


marking of HEMOBLAST Bellows

Conducting pilot study
(27 patients)

The IDE authorizes the launch of a pivotal clinical study of HEMOBLAST Bellows in humans

Inclusion of the first patient in the pivotal clinical study, prospective, randomized, multicentric clinical trial assessing the efficacy and safety of HEMOBLAST Bellows in most types of surgery

Over 150 000 medical devices implanted in Europe


Public funding COLOMATRIX

IDE approval to initiate studies in human patients for HEMOBLAST Bellows

Raised 31,3 M€


Biom’up opens two subsidiaries in the USA and in Germany


marking and launch of the COVAMESH range

Second 510(k) clearance, for the COVAMESH range

Certified to ISO 13485 and ISO 9001 by the SNCH and by the BSI

logo bsi logo snch


marking and launch of the HEMOSNOW range

Second 510(k) clearance, for the COVA ORTHO NERVE

Raised 6,8 M€

Over 100 000 medical devices implanted in Europe


First 510(k) clearance, for the COVA MAX range


Raised 3 M€


marking and launch of the COVA and MATRI ranges


Raised 1,5 M€


Approval and development of the first OEM products


ISO 9001 and ISO 13485 certifications

logo snch


Creation of

Biom'up's Awards

Winners of the Fondation Rhône-Alpes Futur and the Innovact competition awards.
Winners of the Rhône-Alpes Entreprendre Association award and the French National Competition for Creation award in the emerging project category. Biom'up received the French high-tech mutual fund label (FCPI) and became a successful 'Start-Up'.
Winner of the National Competition for Creation award in the creation category; Novacité Labelling.